Shotguns are among a haul of items stolen from Duchy College in Stoke Climsland in the early hours of Friday morning.
In total six guns were taken from from a secure gun cabinet at the specialist agricultural college, near Callington.
Police say the cabinet was removed from the wall and carried to a location around 200m away from the scene. The cabinet door was then forced open and the shotguns were removed.
During the burglary several desktop computers and laptops were also stolen – all of which are security marked.
Police are appealing for witnesses or anyone with information about the burglary to come forward.
A police spokesman said: "Naturally we are concerned that shotguns have been stolen and there are now six unauthorised weapons in the hands of criminals. We have begun a full investigation and we are keen to locate these stolen items as quickly as possible."
"I would urge anyone who is approached with any similar items for sale, where the origin of the items cannot be clearly demonstrated, to contact us straightaway."
If anyone has information in connection with this incident call 101 and quote reference BN/13/166. Alternatively call Crimestoppers anonymously on 0800 555111.
