Throgmorton Cup holders Bodmin Town will begin their defence at home to Camelford on October 25.
The draw for this season's Carlsberg SWPL Throgmorton League Cup competition was made at Tuesday night's AGM.
And Bodmin, who have won the competition the last two seasons, will welcome Premier Division rivals Camelford to Priory Park in a Friday night second round tie.
Draw: First Round (Saturday September 28): Axminster v Appledore; Bovey Tracey v Holsworthy; Bude v Univ of Exeter; Callington v Foxhole; Crediton v Exwick Villa (Fri Sept 27); Exmouth v Budleigh Salterton; Galmpton Utd v Totnes & Dartington; Godolphin v St Dennis; Hayle v Falmouth Tn; Liskeard Ath v Okehampton; Liverton v Plymstock; Mousehole v Helston Ath; Penryn Ath v Porthleven; Penzance v Newquay (Fri Sept 27); Perranporth v Ivybridge; Sidmouth v Cullompton Rgs; Sticker v Newton Abbot Spurs; Stoke Gabriel v Truro City; Teignmouth v Dobwalls; Torpoint v Wadebridge; Vospers OV v Alphington.
Second Round (Saturday October 26): Axminster or Appledore v Exmouth or Budleigh; Bodmin v Camelford (Fri Oct 25); Bovey Tracey or Holsworthy v Torpoint or Wadebridge; Bude or Univ of Exeter v Perranporth or Ivybridge; Crediton or Exwick v Elmore; Elburton v Stoke Gabriel or Truro City; Godolphin or St Dennis v Callington or Foxhole; Hayle or Falmouth v St Blazey; Liskeard or Okehampton v Vospers or Alphington; Mousehole or Helston v Penryn or Porthleven; Plym Parkway v Tavistock (Fri Oct 25); Saltash v Galmpton or Totnes & Dart; Sidmouth or Cullompton v Witheridge; St Austell v Penzance or Newquay (Fri Oct 25); Sticker or Newton Spurs v Liverton or Plymstock; Teignmouth or Dobwalls v Launceston.
